Intratumoral Heterogeneity of 64Cu-ATSM Uptake is a Prognostic Indicator in Patients with Cervical Cancer
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چکیده
منابع مشابه
Prognostic value of preoperative intratumoral FDG uptake heterogeneity in early stage uterine cervical cancer
OBJECTIVE We investigated the prognostic value of intratumoral [¹⁸F]fluorodeoxyglucose (FDG) uptake heterogeneity (IFH) derived from positron emission tomography/computed tomography (PET/CT) in patients with cervical cancer. METHODS Patients with uterine cervical cancer of the International Federation of Obstetrics and Gynecology (FIGO) stage IB to IIA were imaged with [¹⁸F]FDG PET/CT before ...
متن کامل64Cu-ATSM and 18FDG PET uptake and 64Cu-ATSM autoradiography in spontaneous canine tumors: comparison with pimonidazole hypoxia immunohistochemistry
BACKGROUND The aim of this study was to compare (64)Cu-diacetyl-bis(N(4)-methylsemicarbazone) ((64)Cu-ATSM) and (18)FDG PET uptake characteristics and (64)Cu-ATSM autoradiography to pimonidazole immunohistochemistry in spontaneous canine sarcomas and carcinomas. METHODS Biopsies were collected from individual tumors between approximately 3 and 25 hours after the intravenous injection of (64)C...
متن کاملIntratumoral metabolic heterogeneity of cervical cancer.
PURPOSE Previous research has shown that the intertumoral maximum standardized uptake value (SUVMax) of F-18 fluorodeoxyglucose (FDG)-positron emission tomography (PET) for cervical cancer predicts disease outcome. The purpose of this study was to evaluate the pretreatment intratumoral metabolic heterogeneity of FDG. EXPERIMENTAL DESIGN This is a prospective cohort study of 72 patients with I...
متن کاملAn imaging comparison of 64Cu-ATSM and 60Cu-ATSM in cancer of the uterine cervix.
UNLABELLED Tumor uptake of copper(II)-diacetyl-bis(N(4)-methylthiosemicarbazone) (copper-ATSM), a hypoxia-targeting radiopharmaceutical, assessed by PET has been found to correlate with prognosis in several human cancers. Wide clinical utility of this tracer will require its labeling with a copper radionuclide having a longer half-life than the (60)Cu used in studies to date. The purpose of thi...
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ژورنال
عنوان ژورنال: OMICS Journal of Radiology
سال: 2013
ISSN: 2167-7964
DOI: 10.4172/2167-7964.1000130