Intraovarian control of folliculogenesis: Limits to superovulation?
نویسندگان
چکیده
منابع مشابه
Intraovarian control of early folliculogenesis.
Although hormonal regulation of ovarian follicle development has been extensively investigated, most studies concentrate on the development of early antral follicles to the preovulatory stage, leading to the successful use of exogenous FSH for infertility treatment. Accumulating data indicate that preantral follicles are under stringent regulation by FSH and local intraovarian factors, thus pro...
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Background: Opioids may affect hypothalamic GnRH secretion and Hypothalamic-Pituitary- Gonad axis, resulting in reproductive disturbances. Current study investigates the effects of morphine on structure of ovary following superovulalion through morphologic/morphometric studies. Methods: Twelve young female NMRI mice were allocated into treatment and control groups. Treatment group received oral...
متن کاملEpigenetic control of folliculogenesis and luteinization
Folliculogenesis and luteinization are characterized by irreversible and profound physiological and morphological transformation processes, which eventually culminate in the provision of fertilizable eggs and the conversion of the estrogen producing follicle into a progesterone producing corpus luteum. All these processes are preceded by complex alterations of the gene expression profiles in th...
متن کاملIntraovarian regulation of gonadotropin-dependent folliculogenesis depends on notch receptor signaling pathways not involving Delta-like ligand 4 (Dll4)
BACKGROUND In-situ hybridisation studies demonstrate that Notch receptors and ligands are expressed in granulosa cells (GCs) and in the theca layer vasculature of growing follicles. Notch signaling involves cell-to-cell interaction mediated by transmembrane receptors and ligands. This signaling pathway may represent a novel intraovarian regulator of gonadotropin-dependent follicular development...
متن کاملIntraovarian actions of oestrogen.
Oestrogen regulates several hypothalamic and pituitary hormones, which in turn control ovarian functions. Oestrogen and its metabolites, such as catecholoestrogens, also have direct effects within the ovary. This review examines the roles of oestrogen in regulating ovarian folliculogenesis, ovulation and corpus luteum formation. Oestrogen promotes follicular development, which culminates in ovu...
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ژورنال
عنوان ژورنال: Theriogenology
سال: 1984
ISSN: 0093-691X
DOI: 10.1016/0093-691x(84)90310-8