Intramural Great Vessel Lymphoma in a Patient with Left Ventricular Assist Device

IntroductionIntramural Great Vessel lymphoma (IMGVL) is an extremely rare proliferating within the lumina of large vessels like Superior vena cava and Aorta. We present a case IMGVL presenting in patient with Left Ventricular Assist Device (LVAD).Case ReportA 63-year-old male ischemic cardiomyopathy advanced systolic failure supported by LVAD as bridge to transplant, presented clinic complaining claudication symptoms. He has known peripheral vascular disease underwent Aortobifemoral stenting past. Coronary Tomography Angiography (CTA) showed intraluminal thrombus above iliac limbs severe narrowing lumen thought be flow-limiting (Figure 1). mechanical thrombectomy. Intra-operatively, mural near occlusion descending aorta was noted 2). Pathology revealed diffuse B-cell (DLBCL) immunohistochemistry positive for BCL2, MYC, Ki-67 CD20. EBV status negative. A whole-body Positron Emission (PET) scan negative malignancy elsewhere. initiated on chemotherapy.SummaryPrimary subtype extranodal only 4 cases reported literature. It distinct from Intravascular Large Lymphoma (IVLBCL) which limited small vessels. Furthermore, single aortic found autopsy patient, been reported. DLBCL aggressive often requiring combination chemotherapy immune therapy. Long term prognosis our awaiting heart transplant rather uncertain. Intramural (LVAD). chemotherapy. Primary View Image Figure ViewerDownload Hi-res image Download (PPT)