Intracoronary nitroglycerin.

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Failure of Intracoronary Nitroglycerin

Relief of angina by nitroglycerine has been attributed to two possible mechanisms: (1) Increase in myocardial blood supply by direct acton of the drug on the coronary arteries. (2) Reduction in myocardial oxygen demand by action of the drug on the systemic circulation. Sublingual application of nitroglycerin in previous studies did not allow the ruling out of the operation of either or both mec...

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Action of intracoronary nitroglycerin in refractory coronary artery spasm.

Coronary artery spasm usually responds to sublingual nitroglycerin. This report describes four patients with variant angina and one patient with rest angina who had coronary spasm that was refractory to sublingual or i.v. nitroglycerin. In four patients, spasm occurred spontaneous and in one patient after 0.05 mg of ergonovine. In each case, 25-100 micrograms of intracoronary nitroglycerin prom...

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Analysis of coronary responses to various doses of intracoronary nitroglycerin.

We studied the degree of coronary artery dilation resulting from increasing doses of intracoronary nitroglycerin (NTG). Heart rate, aortic pressure and coronary artery angiograms were recorded before and after 5-, 50-, 150- and 250-microgram doses of NTG infused into the left main coronary artery. Coronary artery diameters were measured by a magnification angiographic technique. After intracoro...

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Failure of intracoronary nitroglycerin to alleviate pacing-induced angina.

Relief of angina by nitroglycerine has been attributed to two possible mechanisms: (1) Increase in myocardial blood supply by direct acton of the drug on the coronary arteries. (2) Reduction in myocardial oxygen demand by action of the drug on the systemic circulation. Sublingual application of nitroglycerin in previous studies did not allow the ruling out of the operation of either or both mec...

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Nitroglycerin-induced coronary vasodilation in cardiac transplant recipients. Evaluation with in vivo intracoronary ultrasound.

BACKGROUND Coronary artery vasomotion is altered after cardiac transplantation. The impact of accelerated transplant coronary atherosclerosis and myocardial rejection on vasomotion is not well understood. Intravascular ultrasound is a new imaging method with the ability to study real-time changes in coronary artery dimensions. METHODS AND RESULTS Epicardial coronary artery response to nitrogl...

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ژورنال

عنوان ژورنال: Circulation

سال: 1982

ISSN: 0009-7322,1524-4539

DOI: 10.1161/01.cir.65.5.1040