Intracerebral Hemorrhage Formation Under Direct Oral Anticoagulants
نویسندگان
چکیده
منابع مشابه
Outcome of intracerebral hemorrhage associated with different oral anticoagulants
OBJECTIVE In an international collaborative multicenter pooled analysis, we compared mortality, functional outcome, intracerebral hemorrhage (ICH) volume, and hematoma expansion (HE) between non-vitamin K antagonist oral anticoagulation-related ICH (NOAC-ICH) and vitamin K antagonist-associated ICH (VKA-ICH). METHODS We compared all-cause mortality within 90 days for NOAC-ICH and VKA-ICH usin...
متن کاملVolume and Characteristics of Intracerebral Hemorrhage with Direct Oral Anticoagulants in Comparison with Warfarin
BACKGROUND Patients undergoing anticoagulation therapy often experience intracerebral hemorrhages (ICHs), and warfarin in particular is known to increase hematoma expansion in ICHs, which results in a poor outcome. Recent studies reported that, in comparison with warfarin, direct oral anticoagulants (DOACs) cause fewer ICHs with better functional outcome. However, since it is still unknown whet...
متن کاملOff-Label Use of Direct Oral Anticoagulants in Intracerebral Hemorrhage Patients With Prosthetic Valves.
In this patient, the conventional treatment approach would be to place him back on a vitamin K antagonist (VKA) once the hemorrhage has stabilized and then recommend close monitoring of the international normalized ratio (INR) in the future. However, at times, an unconventional treatment strategy may be best for the patient. In this patient scenario, there are several facts to consider. First, ...
متن کاملComparing intracerebral hemorrhages associated with direct oral anticoagulants or warfarin
OBJECTIVES This cross-sectional survey explored the characteristics and outcomes of direct oral anticoagulant (DOAC)-associated nontraumatic intracerebral hemorrhages (ICHs) by analyzing a large nationwide Japanese discharge database. METHODS We analyzed data from 2,245 patients who experienced ICHs while taking anticoagulants (DOAC: 227; warfarin: 2,018) and were urgently hospitalized at 621...
متن کاملReversal of direct oral anticoagulants
Reversal agents for direct oral anticoagulants (DOACs), including factor X inhibitors and direct thrombin inhibitors, are a major concern in clinical practice. After DOACs were introduced and became widely used as an alternative for vitamin K antagonists in the management of venous thromboembolism and nonvalvular atrial fibrillation, the need for effective reversal agents has increased, particu...
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ژورنال
عنوان ژورنال: Stroke
سال: 2019
ISSN: 0039-2499,1524-4628
DOI: 10.1161/strokeaha.118.023722