Intracellular Localization Map of Human Herpesvirus 8 Proteins
نویسندگان
چکیده
منابع مشابه
Determinants of secretion and intracellular localization of human herpesvirus 8 interleukin-6.
Human herpesvirus 8 (HHV-8) interleukin-6 (vIL-6) is distinct from human and other cellular IL-6 proteins in that it does not require the nonsignaling alpha-receptor subunit for the formation of gp130-based signal transducing complexes and also is largely retained intracellularly rather than being secreted. We and others have reported that vIL-6 is retained and is active in the endoplasmic reti...
متن کامل[Human herpesvirus 8/Kaposi's sarcoma-associated herpesvirus].
Human herpesvirus 8 (HHV-8), a gammaherpesvirus implicated in Kaposi's sarcoma, primary effusion lymphoma, and Castleman's disease, encodes several pathogenically important cellular homologs. To define the HHV-8 transcription program, RNA obtained from latently infected body cavity-based lymphoma 1 cells induced to undergo lytic replication was used to query a custom HHV-8 DNA microarray contai...
متن کاملMultiple human herpesvirus-8 infection.
In Malawian patients with Kaposi sarcoma (KS) and their relatives, we investigated nucleotide-sequence variation in human herpesvirus-8 (HHV-8) subgenomic DNA, amplified from oral and blood samples by use of polymerase chain reaction. Twenty-four people had amplifiable HHV-8 DNA in >1 sample; 9 (38%) were seropositive for human immunodeficiency virus type 1, 21 (88%) were anti-HHV-8-seropositiv...
متن کاملHuman Herpesvirus 8 Seroprevalence, China
To summarize the seroprevalence of human herpesvirus 8 (HHV-8) in mainland China, we conducted a systematic review and meta-analysis based on available literature. Data show that differences in HHV-8 prevalence vary considerably among different ethnic groups and geographic regions. Blood-borne transmission could be a potential route for HHV-8 infection in China.
متن کاملHuman Herpesvirus 8, Southern Siberia
1. Calisher CH, Childs JE, Field HE, Holmes KV, Schountz T. Bats: important reservoir hosts of emerging viruses. Clin Microbiol Rev. 2006;19:531–45. DOI: 10.1128/ CMR.00017-06 2. Wong S, Lau S, Woo P, Yuen K-Y. Bats as a continuing source of emerging infections in humans. Rev Med Virol. 2007;17:67– 91. DOI: 10.1002/rmv.520 3. Wibbelt G, Speck S, Field H. Methods for assessing diseases in bats. ...
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ژورنال
عنوان ژورنال: Journal of Virology
سال: 2008
ISSN: 0022-538X,1098-5514
DOI: 10.1128/jvi.01716-07