Intra-Articular Administration of Cramp into Mouse Knee Joint Exacerbates Experimental Osteoarthritis Progression
نویسندگان
چکیده
منابع مشابه
Intra-articular corticosteroid for knee osteoarthritis.
BACKGROUND Knee osteoarthritis is a leading cause of chronic pain, disability, and decreased quality of life. Despite the long-standing use of intra-articular corticosteroids, there is an ongoing debate about their benefits and safety. This is an update of a Cochrane review first published in 2005. OBJECTIVES To determine the benefits and harms of intra-articular corticosteroids compared with...
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The etiology of pain in osteoarthritis is multifactoral, and includes mechanical and inflammatory processes. Intra-articular injections of hyaluronans (HAs) are indicated when non-pharmacological and simple analgesics have failed to relieve symptoms. The HAs appear to reduce pain by restoring both mechanical and biomechanical homeostasis in the joint. There are five FDA-approved injectable prep...
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Experience from clinical and medicolegal practice has led us to question whether it is still reasonable to supplement an arthroscopic lavage or debridement operation with an intraarticular injection of steroid. We do not suggest that this is common practice but it is clear from new cases seen, and from discussions with trainees, that it occurs sporadically in the UK. A survey in the Trent and Y...
متن کاملIntra-articular injections for osteoarthritis of the knee.
If usual medical measures fail to control the pain of knee osteoarthritis and allow the patient to cope with its symptoms, intra-articular injections of a corticosteroid, a hyaluronan, or both can be tried.
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Osteoarthritis (OA) is an increasingly important public health problem [1]. It is slowly progressive, can cause symptoms ranging from mild to disabiling. Osteoarthritis is a common cause of knee pain especially in the elderly. It is characterised by loss of articular cartilage, subchondral sclerosis, joint deterioration and osteophyte formation [1]. The current treatment for knee OA consists of...
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ژورنال
عنوان ژورنال: International Journal of Molecular Sciences
سال: 2021
ISSN: 1422-0067
DOI: 10.3390/ijms22073429