Intestinal Behçet's Disease in Monozygotic Twins

Coeliac disease in monozygotic twins.

Coeliac disease has a high familial incidence (McCrae, 1969; Walker-Smith, 1973; McNeish and Anderson, 1974; David and Ajdukiewicz, 1975) and the mode of inheritance of susceptibility has been considered to be multifactorial (Robinson et al., 1971). Studies in twins provide an opportunity to explore the relative importance of heredity and environment in the aetiology of the disease. Thus in mon...

[Crohn's disease in monozygotic twins].

A pair of monozygotic twins with Crohn's disease is described. Both have ileocaecal disease and suffered their first symptoms after living apart for 6 years. The pathogenic role of hereditary and environmental factors is discussed in the light of this and previous reports of twins with Crohn's disease.

Huntington's disease in monozygotic twins reared apart.

Monozygotic twins, identical by serological studies, with Huntington's disease are described who were raised in separate households from birth. Age at onset, landmarks of the disease, and behavioural abnormalities were strikingly similar. Previously reported twin studies in Huntington's disease are reviewed. Twin data support the hypothesis that age at onset and several other clinical features ...

Ophthalmic Graves' disease in monozygotic twins.

Crohn ' s disease in monozygotic twins

Seventeen pairs of identical twins concordant for Crohn's disease have been recorded (Table I). We describe a further set of affected twins unusual in that the disease developed simultaneously and at the same site in each patient at a time when they had been living in different environments for 6 years. As in a minority of previous reports (Crismer et al., 1963; Goldstein et al., 1976; Morichau...