Intestinal and extraintestinal manifestations in familial adenomatous polyposis

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[Intestinal and extraintestinal manifestations in familial adenomatous polyposis].

Familijarna adenomatozna polipoza (FAP) je autozomno dominantni polipozni sindrom, odgovoran za pojavu oko 1% svih kolorektalnih karcinoma (CRC) . Ovaj sindrom se ispoljava kod 1/5 000 do 1/17 000 živorođene dece 2, 3 sa stopom penetracije od preko 90% . Zahvata podjednako oba pola i sve geografske lokalitete . Obolele osobe razvijaju 100−5 000 adenoma (prosečan broj adenoma > 1 000) tubularne ...

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extracolonic manifestations in familial adenomatous polyposis

introduction: due to the whole network of polyposis registers worldwide and early prophylactic treatment, survival of familial adenomatosis (fap) patients is improved. extracolonic manifestations are remarkable feature of fap. two extracolonic manifestations (duodenal adenomatosis, leading duodenal cancer and desmoid tumours) play a very important role in the reasons of death in polyposis popul...

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Extra-colonic manifestations of familial adenomatous polyposis.

Familial adenomatous polyposis (FAP) is a genetic disease created by an abnormality of chromosome number five resulting in a generalized cellular growth disorder. The growth abnormality created by the genetic defect dictates the development of benign and malignant lesions in different organs of the body. Even the term familial adenomatous polyposis does not fully describe the defect because les...

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Familial adenomatous polyposis, diagnosis and surveillance strategies: review article

Familial adenomatous polyposis is characterized by over 100 colorectal adenomas in the colorectum. The disease equally affects both sexes, with an incidence estimated at 1.14025-1.8300. The disease is premature in people with familial adenomatous polyposis. Patients suffering from familial adenomatous polyposis have a range of extra-intestinal diseases such as papillae, gastric, small intestine...

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Extracolonic manifestations of familial adenomatous polyposis after proctocolectomy.

HYPOTHESIS Extracolonic manifestations have a major effect on the morbidity and mortality of patients with familial adenomatous polyposis following proctocolectomy. DESIGN Case review study. SETTING Colorectal unit, university-affiliated hospital. PATIENTS Fifty patients (25 males and 25 females) with familial adenomatous polyposis WHO underwent proctocolectomy between January 1988 and Oc...

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ژورنال

عنوان ژورنال: Military Medical and Pharmaceutical Journal of Serbia

سال: 2007

ISSN: 0042-8450,2406-0720

DOI: 10.2298/vsp0707475n