Intestinal absorption of fats

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Intestinal Absorption of Fats.

Great progress in understanding the mechanisms of fat absorption by the mammalian intestine has been made in the past decade and a half. In contrast to the contentions of rival theorists of the century before this, it has been possible for many laboratories throughout the world to confirm observations made by use of the new tools available, and to come to agreement on current interpretations of...

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A Radioautographic Study of Glyceride Synthesis in Vivo during Intestinal Absorption of Fats and Labeled Glucose

Radioautography was used to detect the synthesis of labeled glycerides in intestinal absorptive cells following injections of fatty chyme and glucose-6-H(3) into ligated segments of upper jejunum of fasting rats. Absorption intervals ranged from 2 to 20 min. Labeling is evident throughout the cells in as short a time as 2 min. Most grains are present over droplets of absorbed fat beginning with...

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Investigation of Intestinal Absorption of Pyridinones in Rat

Recently, it has been shown that a number of hydroxypyridinones such as 1,2-dimethyl-3-hydroxypyridin-4-one (L1) are useful for the treatment of iron overload in place of desferrioxamine in thalassaemic patients. In this study, the intestinal absorption (I.A.) of L1 and one of its analogues namely 2-methy-3-hydroxypyridin-4-one (L2), which possesses a higher partition coefficient (Kpart) than L...

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Investigation of Intestinal Absorption of Pyridinones in Rat

Recently, it has been shown that a number of hydroxypyridinones such as 1,2-dimethyl-3-hydroxypyridin-4-one (L1) are useful for the treatment of iron overload in place of desferrioxamine in thalassaemic patients. In this study, the intestinal absorption (I.A.) of L1 and one of its analogues namely 2-methy-3-hydroxypyridin-4-one (L2), which possesses a higher partition coefficient (Kpart) than L...

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INTESTINAL ZINC ABSORPTION IN DESFERROXAMINE-TREATED RATS

Desferroxamine (Desferal) is used tochelate iron in thalassemia, a disease of very high prevalence in various parts of lran. We have investigated intestinal zinc absorption in Desferal-treated rats which, in pilot experiments, showed low serum levels of both iron and zinc. Intraperitoneal administration of ten 0.5 g doses of Desferal (one injection every other day) to male rats produced sev...

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ژورنال

عنوان ژورنال: Journal of Lipid Research

سال: 1964

ISSN: 0022-2275

DOI: 10.1016/s0022-2275(20)40178-6