Interplay between HIV-1 infection and host microRNAs

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چکیده

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Interplay between HIV-1 infection and host microRNAs

Using microRNA array analyses of in vitro HIV-1-infected CD4(+) cells, we find that several host microRNAs are significantly up- or downregulated around the time HIV-1 infection peaks in vitro. While microRNA-223 levels were significantly enriched in HIV-1-infected CD4(+)CD8(-) PBMCs, microRNA-29a/b, microRNA-155 and microRNA-21 levels were significantly reduced. Based on the potential for micr...

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ژورنال

عنوان ژورنال: Nucleic Acids Research

سال: 2011

ISSN: 1362-4962,0305-1048

DOI: 10.1093/nar/gkr961