Intermittent parathyroid hormone treatment can promote linear growth in the ovariectomized growing rat
نویسندگان
چکیده
منابع مشابه
Intermittent parathyroid hormone improve bone microarchitecture of the mandible and femoral head in ovariectomized rats
BACKGROUND Intermittent parathyroid hormone (PTH) can be used to treat osteoporosis of the spine and hip. However, whether it can be used to treat osteoporosis of the mandible is unclear. The purpose of this study was to explore the influence of applying intermittent PTH to ovariectomized rats on the trabecular bone microarchitecture of the mandible and femoral head. METHODS Eighteen female r...
متن کاملEffect of alendronate and intermittent parathyroid hormone on implant fixation in ovariectomized rats.
BACKGROUND Intermittent administration of parathyroid hormone (PTH) leads to bone formation by increasing osteoblast numbers and activity levels. Animal studies have shown that intermittent PTH administration increases implant fixation in normal rats. The purpose of this study was to analyze the osseous incorporation of an implant in osteoporotic rats while treating them with intermittent PTH (...
متن کاملImplant fixation enhanced by intermittent treatment with parathyroid hormone.
The intermittent administration of parathyroid hormone (PTH) increases the formation of bone by stimulating osteoblastic activity. Our study evaluates the possibility that intermittent treatment with PTH (1-34) may also enhance the implant-bone fixation of stainless-steel screws. Twenty-eight rats received one screw in either one (n = 8) or in both (n = 20) proximal tibiae. We administered eith...
متن کاملBisphosphonates can block the deterioration in implant fixation after withdrawal of intermittent doses of parathyroid hormone.
We have examined the deterioration of implant fixation after withdrawal of parathyroid hormone (PTH) in rats. First, the pull-out force for stainless-steel screws in the proximal tibia was measured at different times after withdrawal. The stimulatory effect of PTH on fixation was lost after 16 days. We then studied whether bisphosphonates could block this withdrawal effect. Mechanical and histo...
متن کاملExpression of parathyroid hormone-related protein and the parathyroid hormone/parathyroid hormone-related protein receptor in rat thymic epithelial cells.
Thymic epithelial cells are an important source of cytokines and other regulatory peptides which guide thymocyte proliferation and maturation. Parathyroid hormone-related protein (PTHrP), a cytokine-like peptide, has been reported to affect the proliferation of lymphocytes in vitro. The studies presented here were undertaken to test the hypotheses that PTHrP is produced locally within the thymu...
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ژورنال
عنوان ژورنال: Yonsei Medical Journal
سال: 1999
ISSN: 0513-5796
DOI: 10.3349/ymj.1999.40.2.166