Interleukin-2: Biology, Design and Application

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Biology of interleukin 1.

Interleukin 1 (IL 1) is a polypeptide that is produced after infection, injury, or antigenic challenge. Although the macrophage is a primary source of IL 1, epidermal, epithelial, lymphoid, and vascular tissues synthesize IL 1. When IL 1 gains access to the circulation, it acts like a hormone and induces a broad spectrum of systemic changes in neurological, metabolic, hematologic, and endocrino...

متن کامل

Basic biology and clinical application of specific cyclooxygenase-2 inhibitors.

In summary, COX-2 is a highly regulated gene product that catalyzes the local production of PGs in pathologic and physiologic situations (Figure 1). It is clear that COX-2 is the isoform responsible for production of the PGs that mediate inflammation, pain, and fever. However, the role for COX-2 in normal physiology is still being defined. Specific COX-2 inhibitors represent a significant conce...

متن کامل

Effect of Vitamin D treatment on Interleukin-2 and Interleukin-4 Genes expression in Multiple Sclerosis

Introduction: Multiple sclerosis is a chronic inflammatory disease of central nervous system. The etiology of MS is slightly known, but genetic and environmental factors are reported. Vitamin D regulates gene expression and affects target cell functions. The aim of this study was to investigate the expression variation of IL-2 and IL-4 genes under vitamin D supplementation in patients with mult...

متن کامل

The biology of interleukin-6.

B CELLS ARE the only eukaryotic cells that are able to produce antibody molecules. Their growth and differentiation into antibody producing cells require the presence of T cells and macrophages; the function of these cells was found to be replaced by soluble factors. 3 In the early i980s it was shown that at least two different kinds of factors were required in the regulation of B cell response...

متن کامل

Synthetic biology: biology by design

Correspondence M. A. J. Roberts [email protected] Barts and The London School of Medicine and Dentistry, Queen Mary University of London, Garrod Building, Turner St., Whitechapel, London E1 2AD, UK Prokarium Ltd, Stephenson Building, Keele Science Park, Keele, Staffordshire ST5 5SP, UK The Roslin Institute & Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Trends in Immunology

سال: 2015

ISSN: 1471-4906

DOI: 10.1016/j.it.2015.10.003