Interleukin-12b Polymorphisms in Association With Susceptibility to Severe Sepsis
نویسندگان
چکیده
منابع مشابه
Lack of Association between Interleukin-10 Gene Promoter Polymorphisms with HIV Susceptibility and Progression to AIDS
Background & Objective: Interleukin (IL)-10 is an important anti-inflammatory and immunomodulatory cytokine. Some authors believe that single nucleotide polymorphisms (SNP) in the promoter region of the IL-10 gene have been associated with susceptibility to HIV infection and progression to AIDS, but its role is not clearly defined yet. The present study was undertaken to evaluate the a...
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متن کاملInterleukin-12B & interleukin-10 gene polymorphisms in pulmonary tuberculosis.
BACKGROUND & OBJECTIVE Cytokines play an important role in anti-tuberculosis immune response. Skewing of immunity from protective to pathogenic may involve a shift in Th1-Th2 paradigm. Cytokine gene polymorphism is known to be associated with functional differences in cytokine regulation and altered clinical performance in a variety of diseases. The aim of this study was to know whether Interle...
متن کاملAssociation Study of IL-12B Polymorphisms Susceptibility with Ankylosing Spondylitis in Mainland Han Population
OBJECTIVE This study aims to determine whether the genetic polymorphisms of IL-12B gene is a susceptibility factor to Ankylosing spondylitis (AS) in mainland Han Chinese population. METHOD Eight single-nucleotide polymorphisms (SNPs) (rs10045431, rs11167764, rs3212227, rs6556412, rs6556416, rs6871626, rs6887695 and rs7709212) in the IL-12B gene were genotyped by iMLDR Assay technology in 400 ...
متن کاملlack of association between interleukin-10 gene promoter polymorphisms with hiv susceptibility and progression to aids
background & objective: interleukin (il)-10 is an important anti-inflammatory and immunomodulatory cytokine. some authors believe that single nucleotide polymorphisms (snp) in the promoter region of the il-10 gene have been associated with susceptibility to hiv infection and progression to aids, but its role is not clearly defined yet. the present study was undertaken to evaluate the associ...
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ژورنال
عنوان ژورنال: Laboratory Medicine
سال: 2010
ISSN: 0007-5027,1943-7730
DOI: 10.1309/lmzqbuhfapnr09bq