Interleukin 1 induces human marrow stromal cells in long-term culture to produce granulocyte colony-stimulating factor and macrophage colony- stimulating factor
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Induces Human Marrow Stromal Cells in Long - Term Culture to Granulocyte Colony - Stimulating Factor and Macrophage Colony - Stimulating Factor
(G-CSF) and macnophage CSF (M-CSF) could be identified to in the cultune supernatants. and production of both factors conwas inducible by IL 1 . Shortly after initiation of the longterm marrow cultures “spontaneous” G-CSF and M-CSF release occunred. The release of G-CSF diminished followonce ing addition of the anti-lu 1 antiserum. indicating that the endogenous production of IL 1 by stromal ce...
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ژورنال
عنوان ژورنال: Blood
سال: 1988
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v71.2.430.bloodjournal712430