Interferon-inducible TRIM22 contributes to maintenance of HIV-1 proviral latency in T cell lines
نویسندگان
چکیده
منابع مشابه
Tripartite Motif-Containing Protein 22 Interacts with Class II Transactivator and Orchestrates Its Recruitment in Nuclear Bodies Containing TRIM19/PML and Cyclin T1
Among interferon (IFN) inducible antiviral factors both tripartite motif-containing protein 22 (TRIM22) and class II transactivator (CIITA) share the capacity of repressing human immunodeficiency virus type 1 (HIV-1) proviral transcription. TRIM22 is constitutively expressed in a subset of U937 cell clones poorly permissive to HIV-1 replication, whereas CIITA has been shown to inhibit virus mul...
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1 Department of Microbiology and Immunology, 2 the Lineberger Comprehensive Cancer 9 Center, School of Medicine, The University of North Carolina, Chapel Hill, NC 2759910 729, 3 Key Lab for Infection and Immunity and National Laboratory of 11 Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, 15 Da Tun 12 Road, Chaoyang District, Beijing 100101, China 13 14 *Corresponding ...
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ژورنال
عنوان ژورنال: Virus Research
سال: 2019
ISSN: 0168-1702
DOI: 10.1016/j.virusres.2019.05.009