Interference in Bacterial Quorum Sensing: A Biopharmaceutical Perspective
نویسندگان
چکیده
منابع مشابه
Interference in Bacterial Quorum Sensing: A Biopharmaceutical Perspective
Numerous bacteria utilize molecular communication systems referred to as quorum sensing (QS) to synchronize the expression of certain genes regulating, among other aspects, the expression of virulence factors and the synthesis of biofilm. To achieve this process, bacteria use signaling molecules, known as autoinducers (AIs), as chemical messengers to share information. Naturally occurring strat...
متن کامل5D Bacterial quorum sensing
Quorum sensing is a form of system stimulus and response that is correlated to population density. Many species of bacteria use quorum sensing to coordinate various types of behavior including bioluminescence, biofilm formation, virulence, and antibiotic resistance, based on the local density of the bacterial population [10, 7, 9, 24, 40, 36, 42, 27]. In an analogous fashion, some social insect...
متن کاملMessing with bacterial quorum sensing.
Quorum sensing is widely recognized as an efficient mechanism to regulate expression of specific genes responsible for communal behavior in bacteria. Several bacterial phenotypes essential for the successful establishment of symbiotic, pathogenic, or commensal relationships with eukaryotic hosts, including motility, exopolysaccharide production, biofilm formation, and toxin production, are ofte...
متن کاملBacterial quorum-sensing network architectures.
Quorum sensing is a cell-cell communication process in which bacteria use the production and detection of extracellular chemicals called autoinducers to monitor cell population density. Quorum sensing allows bacteria to synchronize the gene expression of the group, and thus act in unison. Here, we review the mechanisms involved in quorum sensing with a focus on the Vibrio harveyi and Vibrio cho...
متن کاملInterfering with Bacterial Quorum Sensing
Quorum sensing (QS) describes the exchange of chemical signals in bacterial populations to adjust the bacterial phenotypes according to the density of bacterial cells. This serves to express phenotypes that are advantageous for the group and ensure bacterial survival. To do so, bacterial cells synthesize autoinducer (AI) molecules, release them to the environment, and take them up. Thereby, the...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Frontiers in Pharmacology
سال: 2018
ISSN: 1663-9812
DOI: 10.3389/fphar.2018.00203