Interesting things come in small packages

Big things come in small packages

#Microposts2015, the 5th workshop on Making Sense of Microposts, is summarised by the sub-theme: big things come in small packages. The workshop was borne out of research we were each carrying out as microblogging platforms became increasingly popular, and their value as a publishing platform and the data generated as a result began to be recognised. This phenomenon continues to grow, as microb...

Good things come in small packages

Current ovarian cancer treatments based on surgery/chemotherapy show limited efficacy. Targeting immunosuppression is a requirement for the effectiveness of novel promising anti-tumor immunotherapies. Our latest work in preclinical models shows that nanoparticle-mediated delivery of immunostimulatory microRNAs specifically to tumor-associated leukocytes is sufficient to re-program immunological...

Stubby stems: good things come in small packages.

Standard-length porous-coated tapered femoral stems perform exceedingly well in primary total hip arthroplasty (THA) at long-term follow-up. Nevertheless, there are multiple reasons to strongly consider the relatively new concept of short tapered stems. First, there is already a wide variation in the lengths of "standard" components and the ideal length is unknown. The goal of tapered stems is ...

A new model of murine in situ stenting: great things come in small packages.

Drug-eluting stent (DES) therapy has represented a very significant milestone in the evolution of percutaneous coronary intervention (PCI) therapy. DES reduces the need of repeat intervention in the order of 35–70% compare with bare metal stents. However, there is still a need for research aimed at reducing restenosis since the need for re-intervention is not eliminated and certain anatomic and...

Phase-Conversion Nanoparticle Contrast Agents: Do Good Things Come in Small Packages?