Interactions of asymmetric forms of acetylcholinesterase with basement membrane components.
نویسندگان
چکیده
منابع مشابه
Basement membrane components.
I diopathic inflammatory bowel disease (IBD) collectively describes ulcerative colitis (UC) and Crohn’s disease (CD). UC is characterised by inflammation limited to the colonic mucosa and collagen deposition only in the submucosa, whereas CD is characterised by transmural, granulomatous inflammation and thickening of the bowel wall as a result of thickening of the muscularis layers and transmur...
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The interaction between acetylcholinesterase (EC 3.1.1.7) and heparin, a sulphated glycosaminoglycan, was studied by affinity chromatography. A specific binding of the asymmetric acetylcholinesterase to an agarose gel containing covalently bound heparin was demonstrated. This interaction required an intact collagenous tail, shown by the fact that the binding is abolished by pretreatment with co...
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Chick muscle cells differentiating in vitro in the absence of nerve cells produce asymmetric forms of acetylcholinesterase (AChE) only if they originate from muscles which accumulate these forms in ovo (i.e. after embryonic day 5). The presence of nerve cells does not induce the synthesis of A forms in cultures of 5 day-old myoblasts and does not increase their proportion in cultures of 7 day-o...
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A pulse-chase experiment was performed in embryonic rat myotube cultures to examine possible precursor-product relationships among the various molecular forms of acetylcholinesterase (AChE). AChE was labeled with paraoxon, a compound which diethylphosphorylates AChE at its active site. Diethylphosphorylated (labeled) AChE is inactive but can be reactivated by treatment with 1-methyl-2-hydroxyim...
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Sequential extractions of the basement membrane producing Engelbreth-Holm-Swarm tumor yielded heparan sulfate proteoglycans with different size core proteins, but the same size heparan sulfate side chains. Saline, a nondenaturing solvent, extracted a small high density proteoglycan with a heterodisperse core protein of Mr = 95,000-130,000 whereas subsequent extraction with 7 M urea, a denaturin...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1983
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)32126-4