Interaction of OTC drug noscapine and acenocoumarol and phenprocoumon
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چکیده
منابع مشابه
comparative dna interaction studies of antiviral drug, zidovudine and its complex using different instrumental methods
هدف از این مطالعه بررسی امکان استفاده از داروهای شناخته شده در درمان سایر بیماریها به عنوان داروهای ضد سرطان است. همچنین با استفاده از این داروها در ساختمان کمپلکس فلز می توان شاخص های دارویی بدست آمده را بررسی نمود. داروی ضد ویروس ایدز(hiv)به نام زیدوودین(azt)انتخاب و.کمپلکس.محلول.در.آب[pt(azt)2]cl2سنتزو به روشهای مختلف فیزیکی و شیمیایی شناسایی گردید. بر هم کنش مقایسه ای این دارو و کمپلکس پلا...
15 صفحه اولDrug interaction: Omeprazole and Phenprocoumon
BACKGROUND Oral anticoagulants like the coumarin derivatives are characterised by a particularly narrow therapeutic range. Any interfering co-medication can pose a challenge to establishing a stable anticoagulant dosage regimen and thus present a serious risk for the patient. Here we describe two cases of patients on anticoagulant therapy that suggest possible drug interactions between phenproc...
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Coumarin oral anticoagulant drugs have proven to be effective for the prevention of thromboembolic events. World-wide, warfarin is the most prescribed drug. In Europe, acenocoumarol and phenprocoumon are also administered. Yet it has been proven that variant alleles of the VKORC1 and CYP2C9 genotypes influence the pharmacokinetics and pharmacodynamics of these drugs. The combination of these tw...
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W r e a d w i t h i n t e r e s t t h e submission by Sarkar et al in one of the current issue of the journal1 on the subject of our title. Any significant drug interaction particularly with a relatively new drug is worth reporting and a number of such cases strengthen the suspicion. As majori ty of the patients hardly takes a single drug hence a large number of similar adverse reaction with th...
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We had a 61 year old man with n o n H o d g k i n ’ s l y m p h o m a w h o presented with right sided femoral vein thrombosis. He was started on oral acenocoumarol (2 mg OD) with subcutaneous low molecular weight heparin. On 2nd day after starting this, his prothrombin time was 18.9 seconds with INR of 1.3. Then, as he developed a skin ulcer positive for staphylococcus, he was started on oral ...
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ژورنال
عنوان ژورنال: British Journal of Clinical Pharmacology
سال: 2019
ISSN: 0306-5251,1365-2125
DOI: 10.1111/bcp.13887