Interaction of Human Parainfluenza Virus Type 3 Nucleoprotein with Matrix Protein Mediates Internal Viral Protein Assembly
نویسندگان
چکیده
منابع مشابه
Human Parainfluenza Virus Type 3 Matrix Protein Reduces Viral RNA Synthesis of HPIV3 by Regulating Inclusion Body Formation
Human parainfluenza virus type 3 is one of the main causes of lower respiratory illness in newborns and infants. The role of the matrix protein (M) in viral budding is extensively studied, but the effect of M on viral replication remains to be determined. Using an HPIV3 minigenome assay, we found that M reduced HPIV3 mingenome-encoded reporter activity even though it had an unspecific effect on...
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The nucleotide sequence of the matrix (M) gene of human parainfluenza virus 3 (HPIV3), strain 47885, was determined using overlapping cDNA clones derived from mRNA and genomic RNA. The sequence is presented as DNA in the mRNA sense beginning with the first nucleotide of M mRNA. The HPIV3 M gene is 1150 nucleotides long, excluding 5 3'terminal A residues. A single long open reading frame begins ...
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ژورنال
عنوان ژورنال: Journal of Virology
سال: 2016
ISSN: 0022-538X,1098-5514
DOI: 10.1128/jvi.02324-15