Interaction between Neuroendocrinology and Immunology: Hypothalamic-Pituitary-Thyroid Axis in Immunoendocrinology

The study of interactions between neuroendocrinology and immunology, or immunoendocrinology, is a recent field with the majority its development in last 30 years that involves communication nervous, endocrine, immune systems. Homeostasis, development, aging, metabolism, infection, inflammation are all influenced by cross talk these systems via hormones, cytokines, neurotransmitters. nervous system affects through either hypothalamus-pituitary axes (adrenal, gonadal, thyroid, growth-hormone) neuropeptide hormone signals autonomic norepinephrine acetylcholine. On other hand, passes feedback cytokine type concentration blood. Imbalance any leads to increased risk severity metabolic, psychiatric, inflammatory autoimmune diseases. These two complex standalone even more so their interaction. Thus, relationship hypothalamus-pituitary-thyroid axis necessary be reviewed.