Inter-channel scaffolding of presynaptic CaV2.2 via the C terminal PDZ ligand domain
نویسندگان
چکیده
منابع مشابه
Inter-channel scaffolding of presynaptic CaV2.2 via the C terminal PDZ ligand domain
Calcium entry through CaV2.2 calcium channels clustered at the active zone (AZ) of the presynaptic nerve terminal gates synaptic vesicle (SV) fusion and the discharge of neurotransmitters, but the mechanism of channel scaffolding remains poorly understood. Recent studies have implicated the binding of a PDZ ligand domain (PDZ-LD) at the tip of the channel C terminal to a partner PDZ domain on R...
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ژورنال
عنوان ژورنال: Biology Open
سال: 2013
ISSN: 2046-6390
DOI: 10.1242/bio.20134267