Intensive therapy in neonatal tetanus

Neonatal Tetanus in Vietnam: Comprehensive Intensive Care Support Improves Mortality

We report a 66% reduction in neonatal tetanus mortality after introducing a new management bundle integrating antibiotic therapy, muscle relaxation and invasive monitoring. The latter allowed rapid detection of autonomic instability which was treated with magnesium sulphate. This is the first report of its use in neonatal tetanus.

Antimicrobial therapy in neonatal intensive care unit

Severe infections represent the main cause of neonatal mortality accounting for more than one million neonatal deaths worldwide every year. Antibiotics are the most commonly prescribed medications in neonatal intensive care units (NICUs) and in industrialized countries about 1% of neonates are exposed to antibiotic therapy. Sepsis has often nonspecific signs and symptoms and empiric antimicrobi...

Caffeine therapy in neonatal intensive care.

Administration of caffeine is global practice in the prevention of apnoea of prematurity. Apnoea leads to hypoxia, bradycardia and cardiovascular instability. It has significant disease burden in this preterm group. Apnoea of prematurity affects 100% of neonates <28 weeks gestation and approximately 50% of infants 30-32 weeks gestational age. Incidence of apnoea is inversely related to gestatio...

Neonatal tetanus in Casablanca

Neonatal tetanus (NT) remains common in developing countries. Its poor prognosis is characterized by a high mortality rate. Patients and methods – Our retrospective review concerned 50 cases of NT admitted to the intensive care and neonatology units in the Casablanca Children’s Hospital between 1990 and 1999. The diagnosis was made on clinical signs and gravity was evaluated with the Dakar scor...

Eliminating Neonatal Tetanus