INSUSCEPTIBILITY TO SENSITIZATION AND ANAPHYLACTIC SHOCK

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Insusceptibility to Sensitization and Anaphylactic Shock

1. Attempts to produce anaphylactic shock in white rats by second intravenous or subdural injections of horse serum have failed. 2. It was impossible to demonstrate either by skin reactions or by the uterine reaction that white rats can be sensitized to horse serum. 3. It was not possible to sensitize guinea pigs passively with the serum of white rats presumably immunized to horse serum. 4. In ...

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Anaphylactic Shock

Anaphylactic shock is an unexpected, sudden and sometimes deadly event that attacks the patient in 75% of the cases without pre-existent history of allergy. In general, drugs, hymenopteric poisons and nutrients (according to the recent concept) are responsible. Beside the classical IgE-mediated anaphylactic shock there exists another anaphylactic shock, identical in its clinical picture and tre...

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Anaphylactic Shock by Azodyes

Experiments are described which show that anaphylactic shock can be induced in animals sensitized with azoproteins by injecting them with azodyes containing the same azo components as the sensitizing antigen. The anaphylactic reactions are specific and occur with quantities of the dyes as small as fractions of milligrams.

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ژورنال

عنوان ژورنال: Journal of Experimental Medicine

سال: 1922

ISSN: 1540-9538,0022-1007

DOI: 10.1084/jem.36.6.627