Insulin Sensitivity / Insulin Resistance as Predictors of Esophageal Varices in Post Chronic Hepatitis C Virus Patients

Background: Screening of Esophageal Varices (EV) in liver cirrhosis is highly recommended all consensus reports. The standard screening procedure endoscopy. Insulin resistance (IR) and the quantitative insulin sensitivity check index (QUICKI) are reliable predictors portal hypertension. Objective: study aimed to assess compare validity sensitivity/insulin markers other non-invasive for detection EVs post chronic hepatitis C virus cirrhotic patients. Patients Methods: In this cross-sectional study, 76 patients were screened by esophagogastroduodenoscopy abdominal ultrasonography. Estimation fasting serum ELISA technique was carried out. Homeostasis model assessment (HOMA-IR) QUICKI performed. Results: with an advanced grade EV had higher lower QUICKI. A cut-off value HOMA-IR ≥ 3.4 could significantly predict 72% 80.0% specificity. Spleen diameter platelet count/spleen ratio (PC/SD) showed a significant difference among groups. Conclusion: Lower (assessed QUICKI) HOMA IR) good EVs. addition, vein (PV) diameter, spleen PC/SD also found as