Insulin resistance in type I diabetes mellitus: a major role for reduced glucose extraction.
نویسندگان
چکیده
منابع مشابه
Role of glucose transporters in the cellular insulin resistance of type II non-insulin-dependent diabetes mellitus.
To examine the role of glucose transport proteins in cellular insulin resistance, we studied subcutaneous adipocytes isolated from lean control, obese control (body mass index [BMI] 33.4 +/- 0.9), and untreated obese non-insulin-dependent diabetes mellitus (NIDDM) patients (BMI 35.2 +/- 2.1; fasting glucose 269 +/- 20 mg/dl). Glucose transporters were measured in plasma membrane (PM), low-densi...
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Type 2 diabetes mellitus (T2DM) is an insulin resistant state associated with accelerated atherosclerosis, hypertension, dyslipidemia and abnormal vasomotor responses to insulin. One hundred and thirty nine T2DM patients were included in this study. Out of the total 139 patients, 120 (86.33%) had hyper-insulinemia. According to the NCEP-ATP III criteria, the prevalence of IRS was 103 (74.1%) am...
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Objective: Resistance exercise is recommended as effective treatments for people with type 2 diabetes. However, the impact of this mode of exercise on blood glucose, insulin and insulin resistance in Iranian's type 2 diabetic patients is unclear. We conducted a systematic review of the literature for the effect of resistance exercise training on these clinical markers in Iranian's type 2 diabet...
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BACKGROUND Abnormal coronary endothelial reactivity has been demonstrated in diabetes and is associated with an increased rate of cardiovascular events. Our objectives were to investigate the presence of functional coronary circulatory abnormalities over the full spectrum of insulin resistance and to determine whether these would differ in severity with more advanced states of insulin resistanc...
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Introduction: Patients with type 2 diabetes mellitus (DM) are at increased risk of dying from cardiovascular diseases. Elevated cardiovascular risk in this population persists even after other conventional cardiovascular risk factors are eliminated or reduced, suggesting that there are other, incompletely understood, mechanisms which are increasing cardiovascular risk in such patients. Ventricu...
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ژورنال
عنوان ژورنال: The Journal of Clinical Endocrinology & Metabolism
سال: 1996
ISSN: 0021-972X,1945-7197
DOI: 10.1210/jcem.81.2.8636292