Insulin-Like Growth Factor-Binding Protein-1 and Prostate Cancer
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چکیده
منابع مشابه
Insulin-like growth factor-binding protein-1 and prostate cancer.
There is growing and persuasive evidence, both experimental (1–4) and epidemiologic (5–7), that the peptide hormone insulin-like growth factor-I (IGF-I) is a critical factor in the development of prostate cancer. Because of their central role in the regulation of bioavailable IGF-I, the insulin-like growth factor-binding proteins (IGFBPs) have also come under scrutiny as potential mediators of ...
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PURPOSE Laboratory and epidemiological studies suggest that high circulating insulin-like growth factor (IGF)-1 and low IGF binding protein-3 are associated with increased prostate cancer risk. However, the usefulness of serum IGF-1 or IGF binding protein-3 for predicting pathology results in men undergoing prostate biopsy is unclear. We examined the relationships of serum IGF-1, IGF binding pr...
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BACKGROUND Insulin-like growth factors (1GF-1) and insulin-like growth factor binding protein-3 (IGFBP-3) play important roles in cell growth and differentiation. The aim of this work was to investigate the roles of IGF-1 and IGFBP-3 in esophageal cancer. MATERIALS AND METHODS We examined the circulating IGF-1 and IGFBP-3 concentration in 18 healthy controls and 66 esophageal cancer patients ...
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ژورنال
عنوان ژورنال: JNCI Journal of the National Cancer Institute
سال: 1999
ISSN: 0027-8874,1460-2105
DOI: 10.1093/jnci/91.22.1965