Insulin as a surface marker on isolated cells from rat pancreatic islets.

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Insulin as a surface marker on isolated cells from rat pancreatic islets

Immunoreactive insulin was shown to exist as a surface molecule in the plasma membrane of dispersed rat pancreatic islet cells. The intact cells were stained by immunofluorescence with a guinea pig antisera specific for insulin. The hormone on the cell surface could not be accounted for by insulin bound to specific receptors or nonspecifically absorbed to cells. Thus, surface insulin was demons...

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ژورنال

عنوان ژورنال: Journal of Cell Biology

سال: 1983

ISSN: 0021-9525,1540-8140

DOI: 10.1083/jcb.97.2.433