Insights into Peroxisome Function from the Structure of PEX3 in Complex with a Soluble Fragment of PEX19
نویسندگان
چکیده
منابع مشابه
Insights into peroxisome function from the structure of PEX3 in complex with a soluble fragment of PEX19.
The human peroxins PEX3 and PEX19 play a central role in peroxisomal membrane biogenesis. The membrane-anchored PEX3 serves as the receptor for cytosolic PEX19, which in turn recognizes newly synthesized peroxisomal membrane proteins. After delivering these proteins to the peroxisomal membrane, PEX19 is recycled to the cytosol. The molecular mechanisms underlying these processes are not well un...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2010
ISSN: 0021-9258
DOI: 10.1074/jbc.m110.138503