Innovative Formulations for the Controlled and Site-specific Delivery of Antiinflammatory Drugs
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چکیده
منابع مشابه
Lyoprotected nanosphere formulations for paclitaxel controlled delivery.
The preparation and technological characterization of nanosphere formulations (NS) containing the anticancer drug paclitaxel (PTX) are reported. Poly(lactide) (PLA) and poly(lactide-co-glycolide) (PLGA) nanospheres (NS) were prepared by a solvent displacement method. They showed a mean particle size in the range 150-300 nm, with a high homogeneity (polydispersity index < 0.3). For long term sta...
متن کاملINNOVATIVE PHARMACEUTICAL FORMULATIONS AND EXCIPIENTS FOR NASAL DELIVERY OF DRUGS TO TARGET THE SYSTEMIC CIRCULATION Ph.D. thesis
Article history:Received 9 July 2010Received in revised form 31 March 2011Accepted 21 May 2011Available online 1 June 2011
متن کاملLipid-based formulations for oral delivery of lipophilic drugs.
In the last decade there has been a growing interest in lipid-based formulations to deliver challenging compounds such as lipophilic drugs. Following a brief clarification of the nomenclature, this review stresses the different mechanisms of how lipid-based excipients and formulations interact with the absorption process. Case studies are presented in which enhanced bioavailability was demonstr...
متن کاملNanoemulsion Formulations for Improved Oral Delivery of Poorly Soluble Drugs
The objective of this study was to develop nanoemulsion formulations for enhancement of oral bioavailability of paclitaxel, a model hydrophobic drug and P-glycoprotein substrate. The oil-in-water (o/w) nanoemulsions were made with pine nut oil as the internal oil phase, egg lecithin as the primary emulsifier, and water as the external phase. Stearylamine and deoxycholic acid were used to impart...
متن کاملAbstract for the Symposium on Innovative Polymers for Controlled Delivery
for the Symposium on Innovative Polymers for Controlled Delivery 1 TAILOR-MADE COPOLYMERS FOR RESPONSIVE DRUG DELIVERY NANOSYSTEMS Sébastien Cajot, Christine Jérôme Center for Education and Research on Macromolecules (CERM), University of Liege, B6 Sart tilman, B-4000 Liege, Belgium. e-mail: [email protected] Summary Amphiphilic macromolecules combining a biodegradable and a bioeliminable block...
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ژورنال
عنوان ژورنال: Current Pharmaceutical Design
سال: 2013
ISSN: 1381-6128
DOI: 10.2174/138161281941131219124517