Initial activation of cyclin‐B1–cdc2 kinase requires phosphorylation of cyclin B1
نویسندگان
چکیده
منابع مشابه
Translocation of cyclin B1 to the nucleus at prophase requires a phosphorylation-dependent nuclear import signal
BACKGROUND At M phase, cyclin B1 is phosphorylated in the cytoplasmic retention sequence (CRS), which is required for nuclear export. During interphase, cyclin B1 shuttles between the nucleus and the cytoplasm because constitutive nuclear import is counteracted by rapid nuclear export. In M phase, cyclin B moves rapidly into the nucleus coincident with its phosphorylation, an overall movement t...
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ژورنال
عنوان ژورنال: EMBO reports
سال: 2002
ISSN: 1469-221X,1469-3178
DOI: 10.1093/embo-reports/kvf111