Inhibitory potential of Phaseolus lunatus L. Seeds to Digestive Enzymes

Introduction: Study was taken with an objective to investigate the inhibitory effect of Phaseolus lunatus seeds extract on three enzymes (α-amylase, maltase and glucoamylase) which are involved in diabetes. The disadvantages related use synthetic drugs make it necessary search for alternative from medicinal plants. One therapeutic approach treatment postprandial hyperglycaemia is decrease plasma glucose level can be attained by lowering starch hydrolysis digestive such as α-amylase, glucoamylase. antidiabetic agents caused gastrointestinal side effects. Methods: Hence, research aimed evaluate potential inhibit glucoamylase a possible mechanism hypoglycemia this plant less lunatus, also known Lima bean, native Tropical America grown throughout world. bean has been prescribed traditionally treat different diseases including Result: results present study showed that have exerted both time concentration dependent significant these might due cumulative phytoconstituents extract. Conclusion: Therefore, said part mechanisms exhibited its activity through inhibition enzyme.