Inhibitory effects of biochanin A on mouse lung tumor induced by benzo(a)pyrene

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Inhibitory effects of biochanin A on mouse lung tumor induced by benzo(a)pyrene.

Biochanin A, an isoflavone compound, is reported to have an inhibitory effect on benzo(a)pyrene [B(a)P] metabolism. We examined the modifying effect of biochanin A on in vivo carcinogenesis using a mouse lung tumor model. As carcinogens, a single subcutaneous injection of 0.5mg of B(a)P was given within 24 hours after birth. The test groups were injected with 0.125mg of biochanin A in 0.1ml DMS...

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ژورنال

عنوان ژورنال: Journal of Korean Medical Science

سال: 1991

ISSN: 1011-8934,1598-6357

DOI: 10.3346/jkms.1991.6.4.325