Inhibitors of cell proliferation in a rat liver supernatant
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چکیده
منابع مشابه
lOOOOOg-Supernatant Preparations from the Rat Liver
1. The binding of cholic acid to 10000Og supernatants from rat livers was investigated by equilibrium dialysis and gel-exclusion chromatography. 2. Supernatants were found to contain at least two classes of binding site for cholic acid. 3. These receptor molecules are probably proteins since incubation with proteolytic enzymes resulted in complete loss of cholic acid binding. 4. Supernatants we...
متن کاملFactors inhibiting cell proliferation in rat liver cytoplasm.
Two factors from normal rat liver cytoplasm inhibited the proliferation of cultured L-929 fibroblasts. One was arginase, the other was a small molecular weight inhibitor stable to trypsin and heat treatment. The small molecular weight inhibitor inhibited the protein and DNA synthesis of L-cells. Inhibition of DNA synthesis was thought to be secondary to the inhibition of protein synthesis.
متن کاملThe inhibition of rat liver polyribosome breakdown in the presence of liver supernatant.
Rat liver ribosomes prepared from the rapidly sedimenting pellet of a liver homogenate or from the microsomal pellet by the treatment of these pellets with sodium deoxycholate in buffer are deficient in polyribosomes and contain primarily ribosome dimers. Dimer formation can be prevented and a good polyribosome pattern can be obtained from both these pellets provided treatment with sodium deoxy...
متن کاملassessment of the effect of honey as a topical therapy for intra oral wound healing in rat.
چکیده ندارد.
15 صفحه اولBIO treatment enhances rat marrow-derived mesenchymal stem cell in vitro proliferation and viability
Introduction: Previous investigations have indicated that the presence of BIO (6-Bromoindirubin-3-Oxime) in medium of some cell culture enhances the cell proliferation and viability. The aim of the present study was to investigate the BIO effects on in vitro expansion of rat marrow-derived mesenchymal stem cells (MSCs) culture. Methods: In the present experimental study, bone marrow cells from ...
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ژورنال
عنوان ژورنال: Okayama Igakkai Zasshi (Journal of Okayama Medical Association)
سال: 1980
ISSN: 0030-1558,1882-4528
DOI: 10.4044/joma1947.92.1-2_153