INHIBITION STUDIES WITH PYRIMIDINES ON STREPTOCOCCUS FAECALIS R
نویسندگان
چکیده
منابع مشابه
The biosynthesis of thymidylic acid. I. Preliminary studies with extracts of Streptococcus faecalis R.
The biosynthesis of deoxythymidine phosphate from deoxyuridine phosphate has been reported to occur in preparations from animal tissues (l-3) and from Escherichia coli (4). In E. co& the reaction occurs much more rapidly after infection of the cells with bacteriophage (5, 6). In the present paper, it has been demonstrated that Streptococcus faecalis R is also a convenient source of thymidylate ...
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We have previously reported on the tumor inhibitory properties of 5-fluorouracil and 5-fluoroorotic acid (3, 4), prepared by Duschinsky et al. (5), and on the initial clinical trials of 5fluorouracil with patients with far advanced solid tumors (6). The metabolism of 5-fluorouracil and 5-fluororotic acid has been studied, data on excretion and tissue distribution in mice and man have been repor...
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Gale (1) and Epps (2) have reported the properties of an enzyme obtained from various strains of Streptococcus faecalis which decarboxylates tyrosine and dihydroxyphenylalanine. Both of these authors reported that the enzyme preparations, whether made by washing the whole organism, by drying the cells with acetone, or by further purification procedures, were specific to the above two amino acid...
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Identification and susceptibility studies were performed on 301 blood and urine Streptococcus faecalis and Streptococcus faecium isolates. Strep Trio-Tubes S4, S5, and S3 (Carr-Scarborough Microbiologicals, Inc.) were compared with conventional methods for accuracy and rapidity. Of 282 isolates identified as S. faecalis, 98% were identified by species in 4 h with Trio-Tubes; the same percentage...
متن کاملaureus, and Streptococcus faecalis
SYNOPSIS The incidence of trimethoprim resistance in coliforms and multiresistant strains of Staphylococcus aureus isolated in Bristol from 1970 to 1972 is low-2-3 and 1 0% respectively. The resistance is probably intrinsic; there is no evidence that it is R-factor or plasmid mediated. A single mechanism that confers resistance to both trimethoprim and sulphamethoxazole has not been detected. N...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1955
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)71118-6