Inhibition of Tumor Metastasis by Liquid‐Nitrogen‐Shocked Tumor Cells with Oncolytic Viruses Infection (Adv. Mater. 28/2023)

Drug Delivery In article number 2212210, Funan Liu, Hongjun Li, Zhen Gu, and co-workers present an oncolytic virus therapy that can target metastasis after systemic administration. Tumor cells have been pre-infected with serve as the delivery vehicle pathogenicity has eliminated by liquid nitrogen shock, but their metastasis-targeting ability is maintained integrity of cellular structure surface protein preservation. This Trojan-horse-like method prevents neutralization clearance in bloodstream improves tumor-specific delivery.