Inhibiting Wolbachia to treat parasitic diseases
نویسندگان
چکیده
منابع مشابه
Biological and Immunological Reactions in Parasitic Diseases
Processed antigen reacts selectively with lymphocytes bearing .appropriate surface immunoglobulin molecules resulting in the clonal proliferation of these cells, producing circulating immunoglobulin (humoral immunity) or non-circulating immunoglobulins (cellular immunity). High levels of circulating immunoglobulins (lgM & lgG) occur in protozoa and helminths infections. Reaginic antibodies a...
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Protozoa and helminthes can affect the lung as a primary site, or a complication. Some parasites have a migration cycle through the lung (larva migrans), inducing blood and tissue eosinophilia. Clinical manifestations of lung involvement could be acute: asthma –like syndrome, or Loeffler’s syndrome, with dyspnea, wheezing, cough; or chronic such as hemoptysis or right heart failure signs. Acute...
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The parasitic nematodes Wuchereria bancrofti, Brugia malayi and B. timori cause a dreadful disease in humans known as lymphatic filariasis, which afflicts more than 120 million people worldwide. As per recent epidemiologic estimates on prevalence of W. bancrofti and B. malayi, about 428 million people are at risk, with 28 million microfilaria carriers and 21 million clinical cases spread out in...
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Histopathological research is very important in diagnosing human and animal diseases. Detection of histopathological changes during certain parasitic invasions is particularly important for differential diagnosis and often confirms the presence of parasitic diseases. Such studies allow also to conclude on the primary cause of the disease.
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ژورنال
عنوان ژورنال: Nature Reviews Drug Discovery
سال: 2019
ISSN: 1474-1776,1474-1784
DOI: 10.1038/d41573-019-00058-z