Inhaled steroids and mortality in COPD: bias from unaccounted immortal time

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منابع مشابه

Inhaled steroids and mortality in COPD: bias from unaccounted immortal time

1. Rahman I. Reproducibility of oxidative stress biomarkers in breath condensate: are they reliable? Eur Respir J 2004; 23: 183–184. 2. Rosias PPR, Dompeling E, Hendriks HJE, Heijnens JWCM, Donckerwolcke RAMG, Jöbsis Q. Exhaled breath condensate in children: pearls and pitfalls. Pediatr Allergy Immunol 2004; 15: 4–19. 3. Van Hoydonck PGA, Wuyts WA, Vanaudenaerde BM, Schouten EG, Dupont LJ, Temm...

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Inhaled steroids and mortality in COPD: bias from unaccounted immortal time.

A recent observational study, which suggested that inhaled corticosteroids (ICS) with or without long-acting bronchodilators are effective at reducing all-cause mortality in chronic obstructive pulmonary disease (COPD) patients, may be subject to immortal time bias. This bias was assessed using a population-based cohort of 3,524 newly treated COPD patients from Saskatchewan, Canada, observed fr...

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Inhaled steroids in COPD

T he medical community has made up its mind that, although inhaled corticosteroids reduce exacerbations in patients with chronic obstructive pulmonary disease (COPD), they do not affect disease progression. Despite measurement of forced expiratory volume in one second (FEV1) being widely available and a strong predictor of mortality, the emphasis has moved to softer outcome measures which do sh...

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Inhaled steroids and COPD.

1 Warth A, Herpel E, Schmähl A, et al. Mediastinal angiomyolipomas in a male patient affected by tuberous sclerosis. Eur Respir J 2008; 31: 678–680. 2 Johnson SR, Whale CI, Hubbard RB, Lewis SA, Tattersfield AE. Survival and disease progression in UK patients with lymphangioleiomyomatosis. Thorax 2004; 59; 800–803. 3 Cornog JL Jr, Enterline HT. Lymphangiomyoma, a benign lesion of chyliferous ly...

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Inhaled steroids for COPD?

Objectives: To determine the effect of long term inhaled corticosteroids on lung function, exacerbations, and health status in patients with moderate to severe chronic obstructive pulmonary disease. Design: Double blind, placebo controlled study. Setting: Eighteen UK hospitals. Participants: 751 men and women aged between 40 and 75 years with mean forced expiratory volume in one second (FEV1) 5...

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ژورنال

عنوان ژورنال: European Respiratory Journal

سال: 2004

ISSN: 0903-1936,1399-3003

DOI: 10.1183/09031936.04.00062504