Inhalation of steady-state sidestream smoke from one cigarette promotes arteriosclerotic plaque development.

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Inhalation of steady-state sidestream smoke from one cigarette promotes arteriosclerotic plaque development.

BACKGROUND A number of epidemiologic studies have suggested that every year environmental tobacco smoke (second-hand smoke) is responsible for tens of thousands of deaths, mostly from heart disease, in the United States. Environmental tobacco smoke is composed mainly (80% to 85%) of aged and diluted sidestream smoke. The remainder is exhaled mainstream smoke. Among the thousands of compounds th...

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Inhalation of sidestream cigarette smoke accelerates development of arteriosclerotic plaques.

BACKGROUND Environmental tobacco smoke has been blamed for approximately 40,000 excess deaths from heart disease annually in the United States. As yet, no pathophysiological process that could be responsible for these deaths has been identified. Environmental tobacco smoke is composed mainly of aged and diluted sidestream smoke but also contains 15% to 20% exhaled mainstream smoke. Carcinogens,...

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The tar fraction of cigarette smoke does not promote arteriosclerotic plaque development.

In addition to being the single greatest known environmental cause of cancer, cigarette smoke (CS) is also a major contributor to heart disease. We reported previously that 1) inhalation of either mainstream or sidestream CS promotes aortic arteriosclerotic plaque development; 2) 1,3 butadiene, a vapor-phase component of CS, promotes plaque development at 20 ppm, which at the time was only 2 ti...

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Sidestream cigarette smoke and cardiac autonomic regulation

BACKGROUND The literature has already demonstrated that cigarette influences the cardiovascular system. In this study, we performed a literature review in order to investigate the relationship between sidestream cigarette smoke (SSCS) and cardiac autonomic regulation. METHODS Searches were performed on Medline, SciELO, Lilacs and Cochrane databases using the crossing between the key-words: "c...

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Sidestream cigarette smoke toxicity increases with aging and exposure duration.

OBJECTIVES To determine the effects of aging on the toxicity of sidestream tobacco smoke, the complex chemical mixture that enters the air from the lit end of burning cigarettes and constitutes the vast bulk of secondhand smoke. DESIGN Statistical analysis of data from controlled experimental exposures of Sprague Dawley rats to fresh and aged (for more than 30 minutes) sidestream smoke for up...

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ژورنال

عنوان ژورنال: Circulation

سال: 1994

ISSN: 0009-7322,1524-4539

DOI: 10.1161/01.cir.90.3.1363