Influenza virus glycoprotein-reactive human monoclonal antibodies
نویسندگان
چکیده
منابع مشابه
Complement-dependent lysis of influenza a virus-infected cells by broadly cross-reactive human monoclonal antibodies.
We characterized human monoclonal antibodies (MAbs) cloned from influenza virus-infected patients and from influenza vaccine recipients by complement-dependent lysis (CDL) assay. Most MAbs active in CDL were neutralizing, but not all neutralizing MAbs can mediate CDL. Two of the three stalk-specific neutralizing MAbs tested were able to mediate CDL and were more cross-reactive to temporally dis...
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The 3 murine monoclonal antibodies, Yps1, Yps2 and Yps3 reactive to Y. pseudotuberculosis can be stabilized and all were found to be of IgG type. Monoclonal antibody, Yps1, recognized a glycoprotein antigen of the organism with reactivity at the 55-75 kDa region, while Yps2 and Yps3 recognized protein antigens of Y. pseudotuberculosis 65 kDa and 26-28 kDa molecular weight regions, respectively....
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ژورنال
عنوان ژورنال: Microbes and Infection
سال: 2020
ISSN: 1286-4579
DOI: 10.1016/j.micinf.2020.06.003