Influence of the microwave technology on solid dispersions of mefenamic acid and flufenamic acid
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چکیده
منابع مشابه
Influence of the microwave technology on solid dispersions of mefenamic acid and flufenamic acid
The present studies were undertaken to develop solvent-free solid dispersions (SDs) for poorly soluble anti-inflammatory drugs mefenamic acid (MA) and flufenamic acid (FFA) in order to enhance their in vitro dissolution rate and in vivo anti-inflammatory effects. The SDs of MA and FFA were prepared using microwaves irradiation (MW) technique. Different carriers such as Pluronic F127® (PL), Eudr...
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بر اساس نظریه افلاطون در باره شعر خلاقیت هنری مورد انتقاد قرار گرفته است. نظریه کلی در مورد شعر این بود که شعر از ظواهرتقلید میکند و نه حقیقت. چون سایه ای از حقیقت است. اما با پیدایش فلسفه نو افلاطونی، انتقاتات قبلی در مورد شعر و شاعری اصلاح شد. فلوطین در کتاب انئید، اساس خلق هنری را بر محور مُثل افلاطونی قرار داد. وی باور داشت که هنر مندان در خلق آثار هنری، تحت تاثیر مُثل افلاطونی بوده و عوالمی ...
Solid Dispersions of Flufenamic Acid with Peg 4000 and Peg 6000
Non-steroidal anti-inflammatory drugs have an important impact in the actual medicinal therapy, having indications in covering the range from rheumatic inflammations to cardio-vascular, genito-urinary and stomatological diseases. Flufenamic acid is a nonsteroidal anti-inflammatory drug, from the class of fenamates. It exhibits poor aqueous solubility, accordingly the aim of this study was to en...
متن کاملPreparation and investigation of mefenamic acid - polyethylene glycol - sucrose ester solid dispersions.
Mefenamic acid (MA) is a widely used non-steroidal antiinflammatory (NSAID) drug. The adverse effects typical of NSAIDs are also present in the case of MA, partly due to its low water solubility. The aim of this study was to increase the water solubility of MA in order to influence its absorption and bioavailability. Solid dispersions of MA were prepared by the melting method using polyethylene...
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ژورنال
عنوان ژورنال: PLOS ONE
سال: 2017
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0182011