Influence of Process Parameters and Particle Size Distribution on Mechanical Properties of Tablets

The influence of the particle size distribution maltodextrin powders with a dextrose equivalent level 29 as well two tableting process variables, namely compression pressure and dwell time, on tensile strength, porosity, pore final tablet was studied. mechanical strength porosity tablets are assessed in relation to powder parameters. Regarding parameter, it show that compaction clearly has more pronounced compared time range study. As result, study offers better understanding how properties influenced by inter-correlation characteristics Therefore, shelf-life studies downstream processing drug product development will benefit greatly from this work.