Influence of glycaemic index on subjective appetite responses in healthy adults

The glycaemic index (GI) of carbohydrate foods is a useful tool for predicting postprandial glucose and insulin responses(1). Results from human studies suggest an inverse relationship between GI ingested food appetite responses(2). However, evidence on the effects subjective objective satiety responses inconclusive(3). Therefore, aim this study was to assess impact response in humans. We conducted randomised controlled crossover trial 13 adults presenting with normoglycaemia, normal BMI mean age 28.7 ± 6.6 years. Participants were randomly allocated consume high meal (HGI) consisting mashed potatoes, low (LGI) canned whole chickpeas, each providing 50 g total available carbohydrates, after overnight fast. Postprandial captured using visual analogue scale (VAS) 3 domains: hunger, fullness, prospective intake. Plasma ghrelin values also measured by immunoassay (intra-assay variations < 15%), venous blood samples collected over hours following breakfast area under curves (AUCs) calculated trapezoidal method, data analysed t-test statistical significance set at p 0.05. Data are presented as SD. There great observed individual intake both interventions all outcomes illustrated above. hunger significantly lower ingestion LGI (91.2 37.1 mm × h) comparison HGI (113.5 26 (p = 0.035); fullness higher demonstrated AUC hour period (107.3 (80.2 24.7 0.012) respectively. there no significant difference different meals (104.6 41.9 (126.2 26.3 h), In addition, differences > 0.05). The results that positively affects response. hormone unclear possibly due variances hormonal responses.