Influence of cough airflow characteristics on respiratory mucus clearance
نویسندگان
چکیده
A cough is a respiratory reflex for mucus clearance. The airflow dynamics can be characterized by three parameters, which are peak flow rate (CPFR), velocity time (PVT), and expired volume (CEV). In this study, the three-dimensional human airways from generation 0 to 5 reconstructed computerized tomography images. non-Newtonian property of considered. airflow–mucus interaction phenomenon has been analyzed in space based on Eulerian wall film model. maximum air shear stress could reach 38 m/s 14 Pa, respectively, when CPFR 6 L/s. addition, influence CPFR, PVT, CEV clearance studied. efficiency used quantify results showed that increasing no noticeable effect under normal low viscosity. Increasing effectively improve viscosity becomes high. Specifically, an apparent positive clearing regardless thickness. This study provides new research direction improving rather than patients with chronic obstructive pulmonary disease, neuromuscular or other diseases.
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ژورنال
عنوان ژورنال: Physics of Fluids
سال: 2022
ISSN: ['1527-2435', '1089-7666', '1070-6631']
DOI: https://doi.org/10.1063/5.0088100