Influence of Binder Droplet Dimension on Granulation Rate during Fluidized Bed Granulation
نویسندگان
چکیده
منابع مشابه
Influence of binder droplet dimension on granulation rate during fluidized bed granulation.
Here, we statistically identified the critical factor of the granulation rate during the fluidized bed granulation process. Lactose was selected as the excipient and was granulated with several binders, including hydroxypropyl cellulose, hydroxypropyl methyl cellulose, and polyvinylpyrrolidone. The viscosity, density, and surface tension of the binder solution, contact angle, and the work done ...
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I\I: ei:peril1lr~n:al s+;udy 01' f l L!idis2d ~eci 0ranulatiu.l is pre~ent2d. Preliminury ex~e;ililentc, est?~,;lisn the mCl i 1-, variabl'_s in the granulation pr'ocess and er.able a systemc.tic cxperimcr.tal programme to be Jevised. In this programrre, f';ither glass p(jwdel~ Ol~ po,ous alum~na are used as the bed rrateY·ial. The ef'ft~cts of the f:.mdame!1tal fluiciised bed granulation param...
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ژورنال
عنوان ژورنال: Chemical and Pharmaceutical Bulletin
سال: 2013
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.c12-00969