Influence of ABO blood group antigen on activated partial thromboplastin and prothrombin time tests in healthy university students kosti city, White Nile state, Sudan

Background: Variances in blood group antigen have been related with susceptibility particular to diseases. Prothrombin time [PT], measures the efficiency of extrinsic and common coagulation pathways, although Activated partial Thromboplastin [APTT] test evaluates intrinsic pathways. Objective: To explore influence groups on APTT PT among Healthy University Students different ABO groups. Materials methods: Cross section study including student during period three months from September 2020 December at Medical campus, El Imam Mahdi, White Nile State, Kosti City, total 480 students were enrolled. Four milliliters venous was collected each student, grouping done by tile method whereas APTT, analyzed using manual methods. Data processed Statistical Package for Social Sciences (SPSS) program version 26 means descriptive inferential statistics. Results: Blood O largest individuals [45%], followed A [30%] B [16%], while AB has smallest percentage (9%). is significantly higher value [39.07 ± 4.81] second compared [36.60 5.89] second, [35.23 4.86] [34.39 5.30] P < 0.05. Likewise, showed a [15.94 1.36] [14.12 1.43] [13.54 1.35] [14.67 1.80] Male had level (44.44± 7.27] [15.66 1.88] and, female [35.14 6.49] [14.08 1.29] Conclusion: Males levels females. [O] having [A]individuals PT. This proposal that may be affect their (APTT) Coagulation mechanisms (PT].