Inflammatory response to infectious pulmonary injury

Inflammatory response to infectious pulmonary injury.

This review describing the inflammatory response to infectious pulmonary injury is focused on the innate immunity of the distal lung to bacterial pneumonia. The fact that the inflammatory response varies to some extent with the bacterial strain responsible for the infection is emphasised. The key cellular components present in the distal lung are described. The major role of alveolar macrophage...

Hemodynamics modulate pulmonary artery response to injury.

Immunity: The Immune Response to Infectious and Inflammatory Disease

Immunity provides a succinct and straightforward approach to appreciating a complex biological system ridden with intricacies — the immune response. The aim of the text is to guide the readers through the building blocks of the immune system in both health and disease. The early sections of the book detailing the functioning of both the innate and adaptive arm of the immune system provide a fra...

Experimental pulmonary inflammatory injury in the monkey.

Inflammatory pulmonary injury was induced in Macaca mulatta rhesus monkeys by the intrabronchial instillation of the formylated peptide norleu-leu-phe (FNLP) or phorbol myristate acetate (PMA). Indicators of pulmonary injury included an increase in mean protein content of bronchoalveolar lavage (BAL) fluid from 0.51 mg/ml in untreated animals to 3.74 mg/ml and 6.64 mg/ml in FNLP- and PMA-treate...

Age-dependent alterations in the inflammatory response to pulmonary challenge

The aging lung is increasingly susceptible to infectious disease. Changes in pulmonary physiology and function are common in older populations, and in those older than 60 years, pneumonia is the major cause of infectious death. Understanding age-related changes in the innate and adaptive immune systems, and how they affect both pulmonary and systemic responses to pulmonary challenge are critica...