منابع مشابه
Cooperativity in biological systems
Living organisms can sense and respond to external and internal stimuli. Response isdemonstrated in many forms including modulation of gene expression profiles, motility,secretion, cell death, etc. Nevertheless, all forms share a basic property: they depend on sensingsmall changes in the concentration of an effector molecule or subtle conformational changes ina protein and invoking the appropri...
متن کاملInferring Biological Networks
1. Abstract 2. Introduction 3. Computational Approaches for Identifying Gene Modules 3.1. Advanced Statistical Approaches 3.2. Matrix Decomposition Approaches 4. Computational Approaches for Inferring Gene Connectivity 4.1. ODE-based Models 4.2. Bayesian Networks 4.3. Coexpression Networks 4.4. Probabilistic Boolean Networks 4.5. Inference from Multiple Sources of Data 5. Network Analysis in Si...
متن کاملcooperativity in biological systems
living organisms can sense and respond to external and internal stimuli. response isdemonstrated in many forms including modulation of gene expression profiles, motility,secretion, cell death, etc. nevertheless, all forms share a basic property: they depend on sensingsmall changes in the concentration of an effector molecule or subtle conformational changes ina protein and invoking the appropri...
متن کاملDynamic control of catalysis within biological cells
We develop a theory of enzyme catalysis within biological cells where the substrate concentration [S](t) is time dependent, in contrast to the Michaelis-Menten theory that assumes a steady state. We find that the time varying concentration can combine, in a non-linear way, with the ruggedness of the free energy landscape of enzymes (discovered both in single molecule studies and in simulations)...
متن کاملBiological catalysis of mutarotation of glucose.
Bentley, R. & Neuberger, A. (1949). Biochem. J. 45, 584. Campbell, P. N. & Creasy, N. H. (1949). Biochem. J. 44, xl. Cecil, R. & Ogston, A. G. (1948a). Biochem. J. 42, 229. Cecil, R. & Ogston, A. G. (1948b). Biochem. J. 43, 592. Cori, G. T. & Cori, C. F. (1940). J. biol. Chem. 135, 733. Coulthard, C. E., Michaelis, R., Short, W. F., Sykes, G., Skrimshire, G. E. H., Standfast, A. F. B., Birkinsh...
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ژورنال
عنوان ژورنال: IET Systems Biology
سال: 2016
ISSN: 1751-8849,1751-8857
DOI: 10.1049/iet-syb.2015.0087