Infectious reactivation of cytomegalovirus explaining age- and sex-specific patterns of seroprevalence

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Infectious reactivation of cytomegalovirus explaining age- and sex-specific patterns of seroprevalence

Human cytomegalovirus (CMV) is a herpes virus with poorly understood transmission dynamics. Person-to-person transmission is thought to occur primarily through transfer of saliva or urine, but no quantitative estimates are available for the contribution of different infection routes. Using data from a large population-based serological study (n = 5,179), we provide quantitative estimates of key...

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Background and Aims: Cytomegalovirus (CMV) has worldwide distribution, and its prevalence rate depends on factors such as economic and geographical conditions. An important way of the virus transmission is via blood. Due to high prevalence of anti-CMV antibodies in blood donors and lack of data concerning its seroprevalence in the region, this study was carried out to determine the prevalence r...

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ژورنال

عنوان ژورنال: PLOS Computational Biology

سال: 2017

ISSN: 1553-7358

DOI: 10.1371/journal.pcbi.1005719